The Suprachiasmatic Nucleus, Circadian Clocks, and the Liver
نویسنده
چکیده
The circadian clock system adapts phasic physiological activities, such as sleeping and eating, to environmental cycles. The “master clock” is in the suprachiasmatic nucleus (SCN) and the principal cue (Zeitgeber) is the light–dark cycle, around which most mammalian (and those of all living organisms) functions have evolved. In our society, with activity 24 h per day, the clock is frequently overridden or does not match the activity schedule, with increased susceptibility to disease (obesity, type 2 diabetes, and their cardiovascular sequelae) resulting.
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عنوان ژورنال:
دوره 62 شماره
صفحات -
تاریخ انتشار 2013